Methodological Publications

I am always happy to develop methodological work with other statisticians. My contributions to the statistical literature are below.

Phase I Dose Finding

  • Diniz MA, Li Q, Tighiouart M. Dose Finding for Drug Combination in Early Cancer Phase I Trials using Conditional Continual Reassessment Method. Journal of Biometrics & Biostatistics. 2017;8(6). Link and Code.

  • Diniz MA, Kim S, Tighiouart M. A Bayesian adaptive design in cancer phase I trials using dose combinations in the presence of a baseline covariate. Journal of Probability and Statistics. Nov 1;2018:8654173. Link and Code.

  • Diniz MA, Tighiouart M, Rogatko A. Comparison between continuous and discrete doses for model based designs in cancer dose finding. PLoS ONE. 2019 Jan 9;14(1):e0210139. Link and Code.

  • Diniz MA, Kim S, Tighiouart M. A Bayesian Adaptive Design in Cancer Phase I Trials Using Dose Combinations with Ordinal Toxicity Grades. Stats. 2020 Sep;3(3):221-38. Link and Code.

Phase 2 Dose Ranging

  • Diniz MA, Gallardo D, Magalhães tm. Improved inference for MCP-Mod approach using time-to-event endpoints with small sample sizes. Pharmaceutical Statistics. 2023 April 29. Link and [Code]

Adverse Events

  • Gresham G, Diniz MA, Razaee ZS, Luu M, Kim S, Hays RD, Piantadosi S, Tighiouart M, Yothers G, Ganz PA, Rogatko A. Evaluating Treatment Tolerability in Cancer Clinical Trials using the Toxicity Index. JNCI: Journal of the National Cancer Institute. 2020 Dec;112(12):1266-74. Link

  • Razaee ZS, Amini AA, Diniz MA, Tighiouart M, Yothers G, Rogatko A. On the properties of the toxicity index and its statistical efficiency. Statistics in Medicine. 2021 Mar 15;40(6):1535-52. Link

  • Diniz MA, Gresham G, Kim S, Luu M, Henry NL, Tighiouart M, Yothers G, Ganz PA, Rogatko A. Visualizing adverse events using correspondence analysis. BMC Med Res Methodol. 2021. 21, 244. Link

Others

Diniz MA. Statistical methods for validation of predictive models. Journal of Nuclear Cardiology. 2022 May 24:1-8.

Book Chapters

  • Diniz MA, de Bragança Pereira CA, Polpo A. Bayesian semiparametric symmetric models for binary data. In:Interdisciplinary Bayesian Statistics. Springer International Publishing, 2015. 323-335. Link

  • Magalhães TM, Diniz MA. Normality: Assumptions, Transformations and Outliers. In: Lunardi C Adriana (eds) Manual of Clinical Research Applied to Health. Blucher, 2020. 349-364 (In Portuguese) Link

  • Diniz MA, Magalhães TM. Logistic Regression and Related Methods. In: Piantadosi S., Meinert C. (eds) Principles and Practice of Clinical Trials. Springer International Publishing, 2020. Link

  • Jiménez JL, Diniz MA, Rogatko A, Tighiouart M. Designs of Early Phase Cancer Trials with Drug Combinations. In: Modern Statistical Methods for Health Research. Springer, Cham. 2021. 131-160. Link